File:Linezolid metabolism.svg

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Description

The main pathways of linezolid metabolism in humans, showing all metabolites that account for >1% of an excreted dose.

Legend
  1. PNU-142300, accounts for ~10% of excreted dose at steady state
  2. PNU-142586, accounts for ~45% of excreted dose at steady state
  3. PNU-173558, accounts for ~3.3% of excreted dose at steady state
Date
Source Own work, after Slatter JG, Stalker DJ, Feenstra KL, et al. (August 2001). "Pharmacokinetics, metabolism, and excretion of linezolid following an oral dose of [14C]linezolid to healthy human subjects". Drug Metab Dispos 29 (8): 1136–45. PMID 11454733.
Author Fvasconcellos
Permission
(Reusing this file)
Public domain This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.
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15 May 2009

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Date/TimeDimensionsUserComment
current18:13, 15 May 20091,207 × 810 (56 KB)Fvasconcellos{{Information |Description=The main pathways of {{w|linezolid}} metabolism in humans, showing all metabolites that account for >1% of an excreted dose. ;Legend #PNU-142300, accounts for ~10% of excreted dose at {{w|steady state}} #P

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