File:Linear PK Example.png

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Summary

Description
English: Time course of drug plasma concentrations over 96 hours following oral administrations every 24 hours (τ). Absorption half-life 1 h, elimination half-life 12 h. Note that in steady state and in linear pharmacokinetics AUCτ=AUC. Steady state is reached after about 5 × 12 = 60 hours.
Deutsch: Plasmaspiegel über 96 Stunden nach oraler Verabreichung alle 24 Stunden (τ). Absorptionshalbswertzeit 1 h, Eliminationshalbswertzeit 12 h. Im Fließgleichgewicht (Steady state) gilt bei Vorliegen linearer Pharmakokinetik AUCτ=AUC. Der Steady state wird nach etwa 5 Halbwertszeiten (60 h) erreicht.
Date
Source Own work
Author Alfie↑↓© (Helmut Schütz)

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4 April 2011

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Date/TimeDimensionsUserComment
current10:56, 4 April 20111,600 × 1,118 (22 KB)Alfie66Larger font, added doses and dosage interval, average concentration in steady state.

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