English: Potyviridae. Genomic map of a typical member of the genus Potyvirus. The ssRNA genome is represented by a line and the polyprotein ORF by an open box with the mature proteolytic products named. VPg (viral protein genome-linked), the genome-linked viral protein covalently attached to the 5′-terminal nucleotide is represented by a hexagon; P1-Pro (protein 1 protease), a protein with serine proteolytic activity responsible for cleavage at typically Tyr/Phe-Ser (O); HC-Pro (helper component protease), a protein with aphid transmission helper-component activity and cysteine proteolytic activity responsible for cleavage at typically Gly-Gly (◆); P3 (protein 3); PIPO (pretty interesting Potyviridae ORF); 6K (six kilodalton peptide); CI (cytoplasmic inclusion); NIa-Pro (nuclear inclusion A protease), cysteine-like proteolytic activity responsible for cleavage at Gln/Glu-(Ser/Gly/Ala) (↓); Nib (nuclear inclusion B), RNA-dependent RNA polymerase; CP (coat protein). Cleavage sites of P1-Pro, (O), HC-Pro (◆) and NIa-Pro (↓) are indicated.