Antisuppressor
Antisuppressor is a mutation with the response against suppression effects of nonsense suppression or suppression chemicals.[1][2][3][2]
In 1976, Rieger, Michaelis, and Green have been stated:
"antisuppressor – a mutation which countreacts suppressor effects (→ nonsense suppression). Antisuppressor mutations can occur in any of the folowing components affecting the → genetic translation system (Cox 1973):
- A ribosomal component affecting codon-anticodon recognition or tRNA binding.
- A termination factor altered in such a way that synthesis polypeptide release from the ribosome is enhanced thus decreasing the efficiency of suppression.
- An enzyme affecting → suppressor tRNA (either an → aminoacyl-tRNA synthetase, a base modifying enzyme affecting the anticodon, an enzyme modifaying a base or bases involved in ribosome binding, an enzyme affecting tRNA maturation, or a factor controling total tRNA)."[1]
See also
References
- ↑ 1.0 1.1 Rieger, R.; Michaelis, A.; Green, M. M.. Glossary of Genetics and Cytogenetics: Classical and Molecular (1976). Heidelberg - New York: Springer-Verlag. ISBN 3-540-07668-9.
- ↑ 2.0 2.1 King, R. C.; Stansfield, W. D.. Dictionary of Genetics (1998). New York, Oxford: Oxford University Press. ISBN 0-19-50944-1-7.
- ↑ Hadžiselimović, R.; Pojskić, N.. Uvod u humanu imunogenetiku (2005)Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo. ISBN 9958-9344-3-4.