File:DNA DSB TOP2B PARP-1 complex with NHEJ enzymes.jpg
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Summary
| Description |
English: Paused RNA polymerase and limited short-term TOP2B-induced DNA double-strand break. The 5' ends of DNA are covalently joined to tyrosine within the TOP2B dimer complexed with PARP-1. The NHEJ repair pathway components DNA-PKcs, KU70/KU80 and DNA LIGASE IV are also associated with the TOP2B dimer-PARP-1 complex. |
| Date | |
| Source | Own work |
| Author | MethylC5 |
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| Date/Time | Dimensions | User | Comment | |
|---|---|---|---|---|
| current | 13:18, 28 May 2022 | 2,132 × 990 (368 KB) | MethylC5 | Uploaded own work with UploadWizard |
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