File:Gene targeting mechanism vs non homologous end joining.svg
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Summary
| Description |
English: A schematic overview showing the two possible double-strand-break repair mechanisms for DNA after cutting by a site-specific-nuclease such as CRISPR; either the DNA can be repaired by non-homologous end joining (NHEJ) to create random mutations (insertions or deletions, 'indels') at the cut site, or through homologous recombination (HR) with a modified repair template to insert specific edits (short or long sequences) at the cut site. NHEJ will lead to targeted mutagenesis, while HR will lead to Gene Targeting. |
| Date | |
| Source | Own work |
| Author | Yorkrosa |
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| Date/Time | Dimensions | User | Comment | |
|---|---|---|---|---|
| current | 07:28, 16 June 2023 | 5,883 × 1,954 (34 KB) | Yorkrosa | Uploaded own work with UploadWizard |
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