File:Metabolism of psilocybin in humans and mice.png

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Summary

Description
English: Figure caption: "Proposed metabolic pathway of psilocybin and its active metabolite psilocin. Intermediate metabolites are shown in brackets, while putative or not structurally confirmed metabolites are shown in a dotted frame. Metabolites that were only detected in mice are shaded in blue. Major metabolic pathways are marked with bold arrows, while proposed enzymes catalyzing these reactions are indicated next to the arrows. 4-HIA, 4-hydroxyindole-3- acetaldehyde; 4-HIAA, 4-hydroxyindole-3-acetic acid; 4-HTP, 4-hydroxytryptophol; ADH, alcohol dehydrogenase; ALDH, aldehyde dehydrogenase; MAO-A, monoamine oxidase A; UGT, UDP-glucuronosyl transferase."
Date
Source (2024). "In vitro and in vivo metabolism of psilocybin's active metabolite psilocin". Front Pharmacol 15: 1391689. DOI:10.3389/fphar.2024.1391689. PMID 38741590. PMC: 11089204.
Author Jan Thomann, Karolina E. Kolaczynska, Oliver V. Stoeckmann, Deborah Rudin, Patrick Vizeli, Marius C. Hoener, Christopher R. Pryce, Franz X. Vollenweider, Matthias E. Liechti and Urs Duthaler

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Public domain This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.

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Metabolism of psilocybin in humans and mice

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29 April 2024

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Date/TimeDimensionsUserComment
current03:05, 10 February 20251,544 × 1,236 (422 KB)AlyInWikiWonderlandUploaded a work by Jan Thomann, Karolina E. Kolaczynska, Oliver V. Stoeckmann, Deborah Rudin, Patrick Vizeli, Marius C. Hoener, Christopher R. Pryce, Franz X. Vollenweider, Matthias E. Liechti and Urs Duthaler from {{cite journal | vauthors = Thomann J, Kolaczynska KE, Stoeckmann OV, Rudin D, Vizeli P, Hoener MC, Pryce CR, Vollenweider FX, Liechti ME, Duthaler U | title = In vitro and in vivo metabolism of psilocybin's active metabolite psilocin | journal = Front Pharmacol | volume = 15 | iss...

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