Goodpasture syndrome

Goodpasture syndrome (GPS), also known as anti-glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys. This causes bleeding from the lungs and kidney failure.^[1]

Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

Goodpasture Syndrome Media

Diagram of a monomeric (one-unit) antibody

References

↑ Thibaud, V.; Rioux-Leclercq, N.; Vigneau, C.; Morice, S. (December 2019). "Recurrence of Goodpasture syndrome without circulating anti-glomerular basement membrane antibodies after kidney transplant, a case report". BMC Nephrology. 20 (1): 6. doi:10.1186/s12882-018-1197-6. ISSN 1471-2369. PMC 6323659. PMID 30621605.

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[1] Thibaud, V.; Rioux-Leclercq, N.; Vigneau, C.; Morice, S. (December 2019). "Recurrence of Goodpasture syndrome without circulating anti-glomerular basement membrane antibodies after kidney transplant, a case report". BMC Nephrology. 20 (1): 6. doi:10.1186/s12882-018-1197-6. ISSN 1471-2369. PMC 6323659. PMID 30621605.

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