Hexokinase

A picture of hexokinase 1 from the yeast Kluyveromyces lactis^[1].

A hexokinase is an enzyme that phosphorylates (adds phosphyryl groups) hexoses (six-carbon sugars). It takes in a substrate (usually glucose in most organisms) and adds a phosphate (usually from ATP) to form hexose phosphate as the product. When the substrate is glucose, the product is glucose-6-phosphate.

Hexokinase Media

Action of Hexokinase with glucose as substrate.

References

↑ PDB 3O08; Kuettner, E. B.. Crystal structure of dimeric KlHxk1 in crystal form I. RCSB Protein Data Bank (2010)Research Collaboratory for Structural Bioinformatics. doi:10.2210/pdb3o08/pdb. Retrieved 2025-11-07.

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[Kuettner_2010-1] PDB 3O08; Kuettner, E. B.. Crystal structure of dimeric KlHxk1 in crystal form I. RCSB Protein Data Bank (2010)Research Collaboratory for Structural Bioinformatics. doi:10.2210/pdb3o08/pdb. Retrieved 2025-11-07.

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