Kaposi's sarcoma
Kaposi's sarcoma (KS) is a type of cancer that can form masses in the skin, lymph nodes, or other organs. The skin lesions are usually purple in color. They can appear singularly, in a limited area, or be widespread.[6] Lesions may be flat or raised.[4]
| Kaposi's sarcoma, multiple haemorrhagic sarcoma | |
|---|---|
| Other names | Kaposi sarcoma |
| Kaposi sarcoma. Characteristic purple lesions on the nose in an HIV-positive female.[1] | |
| Pronunciation | |
| Symptoms | Purple colored skin lesions[4] |
| Types | Classic, endemic, immunosuppression therapy-related, epidemic[4][5] |
| Risk factors | Human herpesvirus 8 (HHV8), poor immune function[4][6] |
| Diagnostic method | Tissue biopsy, medical imaging[6][4] |
| Differential diagnosis | Blue rubber bleb nevus syndrome, pyogenic granuloma, melanocytic nevi, melanoma[6] |
| Treatment | Surgery, chemotherapy, radiation therapy, biologic therapy[4] |
| Frequency | 42,000 (new cases, 2018)[7] |
| Deaths | 20,000 (2018)[7] |
Kaposi's Sarcoma Media
An example of Kaposi's sarcoma
An HIV-positive person presenting with a Kaposi's sarcoma lesion with an overlying candidiasis infection in their mouth
- Histopathology of Kaposi's sarcoma.png
Micrograph of a Kaposi sarcoma showing its typical features.
- Micrograph of promontory sign of kaposi's sarcoma.jpg
Micrograph of promontory sign in Kaposi's sarcoma in patch stage. Dilated irregular vascular channels surround a pre-existing vessel.
- Micrograph of plaque stage of Kaposi's sarcoma.jpg
Micrograph of plaque stage, with bizarre vessels dissecting the upper dermis. There is erythrocyte extravasation and hemosiderin pigmentation.
- Micrograph of tumor stage of Kaposi's sarcoma.jpg
Micrograph of tumor stage. Well-circumscribed spindle-cell tumor. Erythrocytes lie within poorly defined slit-like vascular spaces.
References
- ↑ Sand, M; Sand, D; Thrandorf, C; Paech, V; Altmeyer, P; Bechara, FG (4 June 2010). "Cutaneous lesions of the nose". Head & Face Medicine. 6 7. doi:10.1186/1746-160X-6-7. PMC 2903548. PMID 20525327.
- ↑ Collins English Dictionary – Complete and Unabridged, 12th Edition 2014. S.v. "Kaposi's sarcoma." Retrieved August 15, 2017 from http://www.thefreedictionary.com/Kaposi's+sarcoma
- ↑ Random House Kernerman Webster’s College Dictionary. S.v. "Kaposi's sarcoma." Retrieved August 15, 2017 from http://www.thefreedictionary.com/Kaposi's+sarcoma
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 "Kaposi Sarcoma Treatment". National Cancer Institute. 16 June 2017.
- ↑ Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).
- ↑ 6.0 6.1 6.2 6.3 Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).
- ↑ 7.0 7.1 The Global Cancer Observatory (2019). "Kaposi sarcoma" (PDF). Retrieved 14 March 2020.