Klinefelter syndrome
Klinefelter syndrome, 47, XXY, or XXY syndrome is a genetic disorder where people have an extra number of X chromosomes.[1] People who have Klinefelter's Syndrome are often called "XXY Males", or "47, XXY Males".[2]
Effects
Males who have this condition are almost always infertile. This means that they cannot father babies.[3]
In other organisms
Any male mammal can have Klinefelter's Syndrome. The mouse is one example.[4] Tortoiseshell or calico markings on male cats are an indicator of Klinefelter's syndrome. These cats are considered to be the model organism for Klinefelter syndrome, because the gene for a cat's orange/black coat markings is found on the X chromosome. [5]
Klinefelter Syndrome Media
- XXY syndrome M.svg
Birth of a cell with karyotype XXY due to a nondisjunction event of one X chromosome from a Y chromosome during meiosis I in the male
- XXY syndrome.svg
Birth of a cell with karyotype XXY due to a nondisjunction event of one X chromosome during meiosis II in the female
References
- ↑ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2005). Robbins and Cotran pathologic basis of disease (7th ed.). Philadelphia: Elsevier/Saunders. ISBN 978-0-7216-0187-8.
- ↑ Bock, Robert (1993). "Understanding Klinefelter Syndrome: A Guide for XXY Males and their Families" (HTML). NIH Pub. No. 93-3202. Office of Research Reporting, NICHD. Retrieved 2007-04-07.
- ↑ Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).
- ↑ Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).
- ↑ Centerwall WR, Benirschke K (1975). "An animal model for the XXY Klinefelter's syndrome in man: Tortoiseshell and calico male cats". American Journal of Veterinary Research. 36 (9): 1275–1280. PMID 1163864.
Other websites
- "Klinefelter Syndrome at the Open Directory Project". dmoz.org. Archived from the original on 24 June 2010. Retrieved 27 July 2010.