Linaclotide
Linaclotide sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere, is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause. It has a black box warning about the risk of serious dehydration in children in the US; the most common adverse effects in others include diarrhea.
Linaclotide Media
- Linaclotide schematic.svg
Schematic structure (protein primary structure) of Linaclotide (Linzess) indicating the disulfide bonds between Cys1 and Cys6, between Cys2 and Cys10, and between Cys5 and Cys13