Neurodegeneration


Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons.

Many neurodegenerative diseases – including amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease.

Such diseases are incurable, resulting in progressive degeneration and/or death of neuron cells.[1]

There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death.[2][3] Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.

Neurodegeneration Media

References

  1. "What is Neurodegenerative Disease?". JPND Research. JPND Research. 17 July 2014. Retrieved February 7, 2015.
  2. Rubinsztein DC (October 2006). "The roles of intracellular protein-degradation pathways in neurodegeneration". Nature. 443 (7113): 780–6. Bibcode:2006Natur.443..780R. doi:10.1038/nature05291. PMID 17051204. S2CID 4411895.
  3. Bredesen DE, Rao RV, Mehlen P (October 2006). "Cell death in the nervous system". Nature. 443 (7113): 796–802. Bibcode:2006Natur.443..796B. doi:10.1038/nature05293. PMC 3970704. PMID 17051206.