Nucleophilic aromatic substitution

Nucleophilic aromatic substitution is a type of chemical reaction in organic chemistry. As the name suggests, it is a reaction where a nucleophile (a chemical with many electrons, that is attracted to chemicals with fewer electrons) substitutes (replaces a functional group) on an aromatic ring.

Aromatic rings are normally nucleophiles, so nucleophilic aromatic substitution only happens in the right conditions. Normally, this is the presence of electron-withdrawing groups in other positions on the ring.

Nucleophilic Aromatic Substitution Media

• Aromatic nucleophilic substitution.svg

  Aromatic nucleophilic substitution

• SNAr mechanism.svg

  SNAr_mechanism

• Aromatic SN1 mechanism.svg

  Aromatic_SN_mechanism

• Substitution via benzyne.svg

  Mechanism of aromatic nucleophilic substitution via benzyne.

• Nucleophilic aromatic substitution 2,4-dinitrochlorobenzene.svg

  Nucleophilic aromatic substitution

• NuArSubPyr.png

  Nucleophilic aromatic substitution at pyridine

• AsymmetricNucleophilicAromaticSubstitution.png

  Asymmetric nucleophilic aromatic substitution