Nucleophilic substitution
A nucleophilic substitution is a chemical reaction. It is a type of substitution, or replacing, reaction. It happens when one nucleophile replaces another one on an atom. The other group leaves the atom and is called a leaving group.[1]
There are different types of nucleophilic substitution. Which type happens depends on the type of the atoms and molecules involved. The two main categories of nucleophilic substitution are the SN1 reaction and the SN2 reaction.
Nucleophilic Substitution Media
A graph showing the relative reactivities of the different alkyl halides towards SN1 and SN2 reactions (also see Table 1).
new example of SN2 rxn, perhaps simpler
SN2 reaction of CH3Cl and Cl-
SN1 reaction mechanism.
1-phenylethylchloride methanolysis
References
- ↑ J. March, Advanced Organic Chemistry, 4th ed., Wiley, New York, 1992.
