Parathyroid hormone
Parathyroid hormone is a hormone which is secreted by the parathyroid glands.[1] These hormones release calcium into the blood to raise calcium levels, making bones stronger. Too little of these hormones can result in hypoparathyroidism and too much of it can lead to hyperparathyroidism.[2]
Parathyroid Hormone Media
helical dimer structure of hPTH-(1-34)
The parathyroid gland releases PTH which keeps calcium in homeostasis.
A diagrammatic representation of the movements of calcium ions into and out of the blood plasma (the central square labeled PLASMA Ca2+) in an adult in calcium balance:The widths of the red arrows indicating movement into and out of the plasma are roughly in proportion to the daily amounts of calcium moved in the indicated directions.The size of the central square in not in proportion to the size of the diagrammatic bone, which represents the calcium present in the skeleton, and contains about 25,000 mmol (or 1 kg) of calcium compared to the 9 mmol (360 mg) dissolved in the blood plasma.The differently colored narrow arrows indicate where the specified hormones act, and their effects (“+” means stimulates; “-“ means inhibits) when their plasma levels are high.PTH is parathyroid hormone, 1,25 OH VIT D3 is calcitriol or 1,25 dihydroxyvitamin D3, and CALCITONIN is a hormone secreted by the thyroid gland when the plasma ionized calcium level is high or rising.The diagram does not show the extremely small amounts of calcium that move into and out of the cells of the body, nor does it indicate the calcium that is bound to the extracellular proteins (in particular the plasma proteins) or to plasma phosphate.
Related pages
References
- ↑ "Gene: PTH (ENSG00000152266) - Summary - Homo sapiens - Ensembl genome browser 89". may2017.archive.ensembl.org.
- ↑ Allerheiligen, DA; Schoeber, J; Houston, RE; Mohl, VK; Wildman, KM (15 April 1998). "Hyperparathyroidism". American Family Physician. 57 (8): 1795–802, 1807–8. PMID 9575320.
