Pemphigus

Pemphigus is an extremly rare skin disease. It happens because the antibodies attack the skin cells. It is an autoimmune disease. It causes blisters and sores on the skin.

There are three types of pemphigus. Pemphigus vulgaris is the most common type. It is more common in Ashkenazi Jews.

Pemphigus Media

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  Microscopic image of direct immunofluorescence using an anti-IgG antibody. The tissue is skin from a patient with Pemphigus vulgaris. Note the intercellular IgG deposits in the epidermis and the early intraepidermal vesicle caused by acantholysis.

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  Pemphigus foliaceus skin eruption on the abdomen of a dog