Reaction intermediate

A reaction intermediate or simply intermediate is a molecule that is formed during a chemical reaction. It is not the final product, but it is something that is more like the product than the reactants. After every step in a reaction mechanism, an intermediate is formed.

Intermediates usually stay around for a little time because they are very reactive. However, it is important not to confuse an intermediate with a transition state. The latter is at a point of maximum energy. An intermediate instead is at a point of minimum energy, i.e. it is a stable molecule. Intermediates can be isolated from a reaction if needed.

For example, in the reaction:

A + B → X → C + D

X is the intermediate. In going from A + B to X and from X to C + D, the reaction will go through a transition state.

Reaction Intermediate Media

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  general E1 elimination eaction