Receptor antagonist

A receptor antagonist is a biological repressor molecule. A receptor antagonist slows down the cell by stopping some of the cell reactions by clogging up the areas that make the cell work. They are sometimes called blockers, such as beta blockers. An antagonist is a ligand which blocks or dampens a biological effect. It acts against an agonist. They may block enzymes or passages through cell membranes.

They are part of the homeostatic system which regulates the body physiology. Some are made for pharmaceutical uses.

Receptor Antagonist Media

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  Antagonists will block the binding of an agonist at a receptor molecule, inhibiting the signal produced by a receptor–agonist coupling.

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  Agonists require higher dose/concentration to achieve the same effect when in the presence of a reversible competitive antagonist.

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  Agonists get its maximum effect reduced when in the presence of an Irreversible Competitive Antagonist or a Reversible Non-Competitive Antagonist.

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  Figure demonstrates the noncompetitive antagonistic behaviour of Phenoxybenzamine on alpha-adrenergiv norepinephrine receptors.

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  Chart demonstrating the difference between agonists, silent antagonists, and inverse agonists.