Toxoplasma

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Toxoplasma gondii is a protozoan parasite that can infect almost all warm-blooded animals, including humans.[1][2]

Toxoplasma gondii
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T. gondii tachyzoites
Scientific classification
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Toxoplasma
Binomial name
Toxoplasma gondii

In humans, it is one of the most common parasites.[3] Blood test show that up to a third of the world population has been or is infected with T. gondii. Infection rates differ greatly from country to country.[4]

Although mild, flu-like symptoms occasionally occur during the first few weeks, infection with T. gondii generally produces no symptoms in healthy human adults.[5] But in infants, HIV/AIDS patients, and others with weakened immunity, infection can cause serious and occasionally fatal illness (toxoplasmosis).[5][2]p77

Infection in humans and other warm-blooded animals can occur

  1. by eating raw or undercooked meat containing T. gondii tissue cysts.[6][7]
  2. by drinking water or eating anything contaminated with oocysts.[8] in the faeces of an infected animal.[7]
  3. from a blood transfusion or organ transplant
  4. or by transmission from mother to foetus across the placenta.[7]

The parasite can only sexually reproduce in the intestines of members of the cat family (felids).[9] Felids are therefore the definitive hosts of T. gondii, with all other hosts defined as 'intermediate hosts'.

References

  1. Weiss, Louis M. & Kami Kim, eds. 2011. Toxoplasma gondii: the model Apicomplexan: perspectives and methods. Academic Press/Elsevier, London, p49.
  2. 2.0 2.1 Dubey J.P. 2010. Toxoplasmosis of animals and humans. 2nd ed, CRC Press. ISBN 978-1-4200-9237-0
  3. "CDC – About Parasites". Retrieved 12 March 2013.
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  5. 5.0 5.1 "CDC Parasites – Toxoplasmosis (Toxoplasma infection) – Disease". Retrieved 12 March 2013.
  6. Tissue cyst = group of cells with a hard shell around them
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  8. Oocyst: a hardy, thick-walled spore able to survive for long periods outside a host. The zygote develops within the spore, which acts to protect it during transfer to new hosts. This method is found in some Apicomplexa.
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