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Trikala is a Greek city and it is one of 51 prefectures of Greece. Trikala is in the center of Greece in the Thessaly periphery. According to the 2001 census, 57,914 people lived there. Trikala is built on a large plain. This plain is one of the biggest plain in Greece. In the west of Trikala is the Pindus range. Trikala is crossed by Litheus river.