Chronic myeloid leukemia
Chronic myeloid leukemia is a chronic (slowly progressive) form of leukemia. It can be treated with Gleevec (Imatinib).[1] Other treatments that are sometimes used include Interferon.[1] Hydroxyurea has also been used,[2] as has Busulfan.[3]
Chronic Myeloid Leukemia Media
Diagram showing the translocation found in the Philadelphia chromosome
Diagram showing the cells CML can develop from
Chronic myeloid leukemia in a 4 years old female. Peripheral blood (MGG stain)
Peripheral blood (MGG stain): marked leukocytosis with granulocyte left shift
A small, hypolobated megakaryocyte (center of field) in a bone marrow aspirate, characteristic of chronic myeloid leukemia.
References
- ↑ 1.0 1.1 "Chronic myelogenous leukemia - Symptoms and causes". Mayo Clinic.
- ↑ Georgii, A.; Heinze, B.; Loffler, H.; Queisser, W.; Hossfeld, D. K.; Pralle, H.; Kolb, H. J.; Hasford, J.; Heimpel, H.; Hehlmann, R. (15 July 1993). "Randomized comparison of busulfan and hydroxyurea in chronic myelogenous leukemia: prolongation of survival by hydroxyurea. The German CML Study Group". Blood. 82 (2): 398–407. doi:10.1182/blood.V82.2.398.398. PMID 8329700 – via www.bloodjournal.org.
- ↑ Djaldetti, Meir; Padeh, Baruch; Pinkhas, Jack; De Vries, Andre (1966). "Prolonged Remission in Chronic Myeloid Leukemia after One Course of Busulfan" (PDF). Blood. 27 (1): 103–109. doi:10.1182/blood.V27.1.103.103. PMID 5216460.