Chronic myeloid leukemia
Chronic myeloid leukemia is a chronic (slowly progressive) form of leukemia.
Treatment
It can be treated with Gleevec (Imatinib).[1] Other treatments that are sometimes used include Interferon.[1] Hydroxyurea has also been used,[2] as has Busulfan.[3]
Chronic Myeloid Leukemia Media
Diagram showing the translocation found in the Philadelphia chromosome
Diagram showing the cells CML can develop from
Chronic myeloid leukemia in a 4 years old female. Peripheral blood (MGG stain)
Peripheral blood (MGG stain): marked leukocytosis with granulocyte left shift
A small, hypolobated megakaryocyte (center of field) in a bone marrow aspirate, characteristic of chronic myeloid leukemia.
References
- ↑ 1.0 1.1 Chronic myelogenous leukemia - Symptoms and causes. Mayo Clinic.
- ↑ Georgii, A.. Randomized comparison of busulfan and hydroxyurea in chronic myelogenous leukemia: prolongation of survival by hydroxyurea. The German CML Study Group. Blood 82 (2) (15 July 1993). p. 398–407. doi:10.1182/blood.V82.2.398.398.
- ↑ Djaldetti, Meir. Prolonged Remission in Chronic Myeloid Leukemia after One Course of Busulfan. Blood 27 (1) (1966). p. 103–109. doi:10.1182/blood.V27.1.103.103.