Co-amoxiclav

Co-amoxiclav is an antibiotic that is also known as Amoxicillin/clavulanic acid. It is used to treat bacterial infections such as pneumonia, animal bites, urinary tract infections. The antibiotic is also used in veterinary practices and is commonly given to farm animals and pets against similar infections. It's brand name in the UK is Augmentin and is only available on prescription.^[1]

Resistance

Because the antibiotic is used widely amongst humans and animals, bacterial resistance to this antibiotic is growing.^[2]

History

Co-amoxiclav was identified in 1972 by a group of scientists in Beecham (now GlaxoSmithKline). It was launched as Augmentin in the UK in 1981 and it is a combination of clavulanic acid and Amoxicillin.^[3] It is now on the World Health Organisation's list of Essential Medicines meaning it is very important in modern medicine.^[4]

Side effects

As with most antibiotics, some side effects of Co-amoxiclav include vomiting, diarrhea and headaches. A history of problems with penicillin is also an indicator that Co-amoxiclav should not be taken.^[5]

References

↑ "Co-amoxiclav: antibiotic to treat infections". nhs.uk. 2022-09-26. Retrieved 2023-07-01.
↑ Choraine, P. (2010-06-10). "Antibiotic resistance and prudent use of antibiotics in veterinary medicine". Equine Veterinary Education. 12 (2): 108–112. doi:10.1111/j.2042-3292.2000.tb01773.x. ISSN 0957-7734.
↑ Geddes, Alasdair M.; Klugman, Keith P.; Rolinson, George N. (December 2007). "Introduction: historical perspective and development of amoxicillin/clavulanate". International Journal of Antimicrobial Agents. 30: 109–112. doi:10.1016/j.ijantimicag.2007.07.015. ISSN 0924-8579.
↑ "World Health Organization model list of essential medicines for children". Yearbook of Paediatric Endocrinology. 2022-09-12. doi:10.1530/ey.19.13.1. ISSN 1662-4009.
↑ World Health Organization; Stuart, Marc C; Kouimtzi, Maria; Hill, Suzanne (2009). "WHO model formulary 2008 / editors: Marc C. Stuart, Maria Kouimtzi, Suzanne R. Hill": 634. ISBN 9789241547659. {{cite journal}}: Cite journal requires |journal= (help)

[1] "Co-amoxiclav: antibiotic to treat infections". nhs.uk. 2022-09-26. Retrieved 2023-07-01.

[2] Choraine, P. (2010-06-10). "Antibiotic resistance and prudent use of antibiotics in veterinary medicine". Equine Veterinary Education. 12 (2): 108–112. doi:10.1111/j.2042-3292.2000.tb01773.x. ISSN 0957-7734.

[3] Geddes, Alasdair M.; Klugman, Keith P.; Rolinson, George N. (December 2007). "Introduction: historical perspective and development of amoxicillin/clavulanate". International Journal of Antimicrobial Agents. 30: 109–112. doi:10.1016/j.ijantimicag.2007.07.015. ISSN 0924-8579.

[4] "World Health Organization model list of essential medicines for children". Yearbook of Paediatric Endocrinology. 2022-09-12. doi:10.1530/ey.19.13.1. ISSN 1662-4009.

[5] World Health Organization; Stuart, Marc C; Kouimtzi, Maria; Hill, Suzanne (2009). "WHO model formulary 2008 / editors: Marc C. Stuart, Maria Kouimtzi, Suzanne R. Hill": 634. ISBN 9789241547659. {{cite journal}}: Cite journal requires |journal= (help)

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