Cyclopia
Cyclopia (also called cyclocephaly or synophthalmia) is a birth defect. Cyclopia is characterized by a failure of the prosencephalon to separate the two orbits (eyes). This leads to the formation of a central deformed eye and an absence of a nasal cavity.[1] It causes can be either genetic, or as a result of an exposure to poisons.[2] The term "cyclopia" comes from Cyclops, a giant one-eyed creature the Greek Greek mythology.[3]
Babies with Cyclopia rarely live longer than one day.
Cyclopia Media
A Swedish description from 1793 of a newborn with cyclopia
Page 20 of the book Les écarts de la nature
- ABNORMALITIES:*Vrolik, Willem 1801-1863.*Tabulae ad illustrandum embryogenesin hominis et*mammalium, tam naturalem quam abnormen [De vrucht*van den mensch en van de zoogdieren, etc / Auctore*W. Vrolik. Amstelodami : G.M.P. Londonck, 1849*Plate LVI. fig. 1. Rare Books*Keywords: epb /d/vro; ABNORMALITIES
- Dog with congenital defects. Lithograph. Iconographic Collections
- Head of a donkey with a congenitally deformed head. Lithograph. Iconographic Collections
Sheep with in utero cyclopamine exposure
A pig at the Hunterian Museum, Glasgow
References
- ↑ Garzozi, H. J.. Case of True Cyclopia. The British Journal of Ophthalmology 69 (4) (1985). p. 307–311. doi:10.1136/bjo.69.4.307.
- ↑ Rufas O. Howard. Chromosomal Abnormalities Assosiated with Cyclopia and Synophthalmia. Transactions of the American Ophthalmological Society 75 (1977). p. 505–538.
- ↑ Developmental biology: from a cell to an organism (2009)Infobase Publishing. p. 107. ISBN 9781438126302.