Irritable bowel syndrome

Jump to navigation Jump to search
Irritable bowel syndrome
Other namesSpastic colon, nervous colon, mucous colitis, spastic bowel[1]
Irritable bowel syndrome.jpg
3D depiction of the pain of IBS
SymptomsDiarrhea, constipation, abdominal pain[1]
Usual onsetBefore 45 years old[1]
DurationLong term[2]
CausesUnknown[2]
Risk factorsGenetic predisposition,[3] psychological stress,[4]
childhood abuse,
food poisoning,[5]
psychiatric illness[6]
Diagnostic methodBased on symptoms, exclusion of other diseases
Differential diagnosisCeliac disease, giardiasis, non-celiac gluten sensitivity, microscopic colitis, inflammatory bowel disease, small intestine bacterial overgrowth, bile acid malabsorption, colon cancer
TreatmentSymptomatic (dietary changes, medication, human milk oligosaccharides, probiotics, counseling)
PrognosisNormal life expectancy
Frequency10–15% (developed world) and 15–45% (globally)

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder by a group of symptoms that usually include abdominal pain, abdominal bloating and changes in bowel movements.[1] These symptoms may happen over a long time, sometimes for years.[2] IBS can affect quality of life and may impact daily life activities.[7] Disorders such as anxiety, major depression, and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are common among people with IBS.[1][8][note 1][9]

The cause of IBS is not known, but it can be triggered by stress,[10] or an intestinal infection.[11]

Irritable Bowel Syndrome Media

Notes

  1. ↑ The cited review is based on sources ranging from 1988 to 2001 and is probably biased relative to a more recent research.

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Definition and Facts for Irritable Bowel Syndrome. NIDDKD (23 February 2015). Retrieved 29 March 2016.
  2. ↑ 2.0 2.1 2.2 Symptoms and Causes of Irritable Bowel Syndrome. NIDDK (23 February 2015). Retrieved 29 March 2016.
  3. ↑ Rifaximin for Irritable Bowel Syndrome: A Meta-Analysis of Randomized Placebo-Controlled Trials. Medicine 95 (4) (January 2016). doi:10.1097/MD.0000000000002534.
  4. ↑ Brain-gut response to stress and cholinergic stimulation in irritable bowel syndrome. A preliminary study. Journal of Clinical Gastroenterology 17 (2) (September 1993). p. 133–41. doi:10.1097/00004836-199309000-00009.
  5. ↑ Post Infectious IBS - About IBS (March 8, 2021).
  6. ↑ New insights in the etiology and pathophysiology of irritable bowel syndrome: contribution of neonatal stress models. Pediatric Research 62 (3) (September 2007). p. 240–5. doi:10.1203/PDR.0b013e3180db2949.
  7. ↑ The burden of illness of irritable bowel syndrome: current challenges and hope for the future. Journal of Managed Care Pharmacy 10 (4) (2004). p. 299–309. doi:10.18553/jmcp.2004.10.4.299.
  8. ↑ Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?. Gastroenterology 122 (4) (April 2002). p. 1140–56. doi:10.1053/gast.2002.32392.
  9. ↑ Irritable bowel syndrome - Symptoms and causes (in en). Mayo Clinic. Retrieved 2023-12-05.
  10. ↑ The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome. Gastroenterology 140 (3) (March 2011). p. 761–5. doi:10.1053/j.gastro.2011.01.032.
  11. ↑ Postinfectious irritable bowel syndrome. Gastroenterology 136 (6) (May 2009). p. 1979–88. doi:10.1053/j.gastro.2009.02.074.