Irritable bowel syndrome
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder by a group of symptoms that usually include abdominal pain, abdominal bloating and changes in bowel movements.[1] These symptoms may happen over a long time, sometimes for years.[2] IBS can affect quality of life and may impact daily life activities.[7] Disorders such as anxiety, major depression, and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are common among people with IBS.[1][8][note 1][9]
| Irritable bowel syndrome | |
|---|---|
| Other names | Spastic colon, nervous colon, mucous colitis, spastic bowel[1] |
 | |
| 3D depiction of the pain of IBS | |
| Symptoms | Diarrhea, constipation, abdominal pain[1] |
| Usual onset | Before 45 years old[1] |
| Duration | Long term[2] |
| Causes | Unknown[2] |
| Risk factors | Genetic predisposition,[3] psychological stress,[4] childhood abuse, food poisoning,[5] psychiatric illness[6] |
| Diagnostic method | Based on symptoms, exclusion of other diseases |
| Differential diagnosis | Celiac disease, giardiasis, non-celiac gluten sensitivity, microscopic colitis, inflammatory bowel disease, small intestine bacterial overgrowth, bile acid malabsorption, colon cancer |
| Treatment | Symptomatic (dietary changes, medication, human milk oligosaccharides, probiotics, counseling) |
| Prognosis | Normal life expectancy |
| Frequency | 10–15% (developed world) and 15–45% (globally) |
The cause of IBS is not known, but it can be triggered by stress,[10] or an intestinal infection.[11]
Irritable Bowel Syndrome Media
Prevalence of protozoal infections in industrialized countries (United States and Canada) in the 21st century
Percentage of population with IBS reported in various studies in different countries (see sources in the table)
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Notes
- ↑ The cited review is based on sources ranging from 1988 to 2001 and is probably biased relative to a more recent research.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Definition and Facts for Irritable Bowel Syndrome. NIDDKD (23 February 2015). Retrieved 29 March 2016.
- ↑ 2.0 2.1 2.2 Symptoms and Causes of Irritable Bowel Syndrome. NIDDK (23 February 2015). Retrieved 29 March 2016.
- ↑ Rifaximin for Irritable Bowel Syndrome: A Meta-Analysis of Randomized Placebo-Controlled Trials. Medicine 95 (4) (January 2016). p. e2534. doi:10.1097/MD.0000000000002534.
- ↑ Brain-gut response to stress and cholinergic stimulation in irritable bowel syndrome. A preliminary study. Journal of Clinical Gastroenterology 17 (2) (September 1993). p. 133–41. doi:10.1097/00004836-199309000-00009.
- ↑ Post Infectious IBS - About IBS (March 8, 2021).
- ↑ New insights in the etiology and pathophysiology of irritable bowel syndrome: contribution of neonatal stress models. Pediatric Research 62 (3) (September 2007). p. 240–5. doi:10.1203/PDR.0b013e3180db2949.
- ↑ The burden of illness of irritable bowel syndrome: current challenges and hope for the future. Journal of Managed Care Pharmacy 10 (4) (2004). p. 299–309. doi:10.18553/jmcp.2004.10.4.299.
- ↑ Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?. Gastroenterology 122 (4) (April 2002). p. 1140–56. doi:10.1053/gast.2002.32392.
- ↑ Irritable bowel syndrome - Symptoms and causes (in en). Mayo Clinic. Retrieved 2023-12-05.
- ↑ The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome. Gastroenterology 140 (3) (March 2011). p. 761–5. doi:10.1053/j.gastro.2011.01.032.
- ↑ Postinfectious irritable bowel syndrome. Gastroenterology 136 (6) (May 2009). p. 1979–88. doi:10.1053/j.gastro.2009.02.074.
