Mobile genetic elements
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Mobile genetic elements (MGE) are a type of DNA that can move around within the genome. They include:
- Transposons (also called transposable elements)
- Plasmids
- Bacteriophage elements, like Mu which integrates randomly into the genome
- Group II introns
The total of all mobile genetic elements in a genome may be referred to as the mobilome.
Barbara McClintock was awarded the 1983 Nobel Prize in Physiology or Medicine "for her discovery of mobile genetic elements".[1]
Mobile Genetic Elements Media
Transposition of target sequence into recombination site in DNA by Transposase. Replication of the transposable sequence starts to occur when transposase cuts single strands on opposite sides of the dsDNA. The replication is completed in the transposon complex and excised to target sequence for recombination.
Related pages
References
- ↑ "The Nobel Prize in Physiology or Medicine 1983". nobelprize.org. Retrieved 14 July 2010.
- Miller W.J. and Capy P. (eds) 2004. Mobile genetic elements : protocols and genomic applications. Humana Press. ISBN 1-58829-007-7
- Shapiro J.A. (ed) 1983. Mobile genetic elements. Academic Press. ISBN 0-12-638680-3