Pathogen
A pathogen is an infectious thing, such as a virus, bacteria, fungi or parasite, which causes a disease. This ability is called pathogenicity.
The body has many ways to defend against some of the common pathogens (such as Pneumocystis) in the form of the human immune system and by some "helpful" bacteria present in the human body's normal human flora. However, if the immune system or "good" bacteria is damaged in any way (for example, chemotherapy, HIV, or antibiotics being taken to kill other pathogens), pathogenic bacteria that were being held back can grow and cause harm to the host. Such cases are opportunistic infections.
Some pathogens cause epidemics. These include the bacterium Yersinia pestis which may have caused the Black Death, the Variola virus, and the malarial protozoa. They hurt or even kill large numbers of people.
The most famous and lethal outbreak was the 1918 Spanish flu pandemic (type A influenza, H1N1 subtype), which lasted from 1918 to 1919. It is not known exactly how many it killed, but estimates range from 20 to 100 million people.[1][2] This pandemic has been described as "the greatest medical holocaust in history" and may have killed as many people as the Black Death.[3]
The huge death toll was caused by an extremely high infection rate of up to 50% and the extreme severity of the symptoms. One observer wrote, "One of the most striking of the complications was hemorrhage from mucous membranes, especially from the nose, stomach, and intestine. Bleeding from the ears and skin also occurred".[1] The majority of deaths were from bacterial pneumonia, a secondary infection caused by influenza, but the virus also killed people directly, causing massive bleeding and oedema in the lungs.[4]
In plants, fungi are the main cause of infectious disease.
Pathogen Media
A photomicrograph of a stool that has shigella dysentery. These bacteria typically cause foodborne illness.
- Variant Creutzfeldt-Jakob disease (vCJD), H&E.jpg
Magnified 100× and stained. This photomicrograph of the brain tissue shows the presence of the prominent spongiotic changes in the cortex, with the loss of neurons in a case of a variant of Creutzfeldt-Jakob disease (vCJD).
- Threadworm.jpg
Two pinworms next to a ruler, measuring 6 millimeters in length
- Brown Rot on Apple.jpg
Brown rot fungal disease on an apple. Brown rot typically target a variety of top-fruits.
A structure of Doxycycline a tetracycline-class antibiotic
References
- ↑ 1.0 1.1 Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).
- ↑ Patterson, K. D.; Pyle, G. F. (Spring 1991). "The geography and mortality of the 1918 influenza pandemic". Bull Hist Med. 65 (1): 4–21. PMID 2021692.
- ↑ Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).
- ↑ Lua error in Module:Citation/CS1/Identifiers at line 630: attempt to index field 'known_free_doi_registrants_t' (a nil value).