Raphe nuclei
The Raphe nuclei (singular = Raphe nucleus) are a cluster of nuclei in the hindbrain which release a neurotransmitter called serotonin (5-HT). The serotonin molecules get sent all over the brain, where they're needed for all sorts of roles.[1] 'Selective serotonin reuptake inhibitor' (SSRI) antidepressants are believed to act in these nuclei, as well as at their targets.[2] Many opioids (drugs that calm people down) can act on the Raphe nuclei to secrete too much 5-HT.
Raphe Nuclei Media
Dopamine and serotonin pathways in the brain
References
- ↑ Basic neurochemistry (1999)Lippincott Williams and Wilkins. ISBN 0-397-51820-X.
- ↑ Briley, M. Neurobiological mechanisms involved in antidepressant therapies. Clin Neuropharmacol 16 (5) (October 1993). p. 387–400. doi:10.1097/00002826-199310000-00002.