Sédhiou is a region in the southwest of Senegal. The regional capital is Sédhiou. It was created in 2008.
As of the 2013 census, 434,877 people lived there. It has an area of 7,341 km2 (2,834 sq mi).
There are three départements:
Coordinates: 12°42′N 15°33′W / 12.700°N 15.550°W / 12.700; -15.550