Changes

</ref> They switch on cell-surface receptors which activate [[T cell]]s and [[B cell]]s to start and shape the [[Adaptive immune system|adaptive immune response]].

</ref> They switch on cell-surface receptors which activate [[T cell]]s and [[B cell]]s to start and shape the [[Adaptive immune system|adaptive immune response]].

== History ==

== History ==

Dendritic cells were first described by [[Paul Langerhans]] (Langerhans cells) in the late nineteenth century. It wasn't until 1973, however, that [[Ralph Steinman]] and Zanvil  Cohn gave them the name 'dendritic cells'.<ref name=Steinman>{{cite journal |author=Steinman R.M. & Cohn Z.A. |title=Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution |journal=J. Exp. Med. |volume=137 |issue=5 |pages=1142–62 |year=1973 |pmid=4573839|doi=10.1084/jem.137.5.1142 |pmc=2139237}}</ref> For discovering the central role of dendritic cells in the adaptive immune response,<ref name="pmid9521319">{{cite journal |author=Banchereau J. & Steinman R.M. |title=Dendritic cells and the control of immunity |journal=Nature |volume=392 |issue=6673 |pages=245–52 |year=1998 |pmid=9521319 |doi=10.1038/32588 |s2cid=4388748 }}</ref> Steinman was awarded the [[Albert Lasker Award]] in 2007,<ref name="Lasker2007">{{cite web |url=http://www.laskerfoundation.org/awards/2007basic.htm |title=The Lasker Foundation - 2007 Awards |access-date=2010-11-27}}</ref> and the [[Nobel Prize in Physiology or Medicine]] in 2011.<ref name="Nobel2011">{{cite web |url=http://www.nobelprize.org/nobel_prizes/medicine/laureates/2011/# |title=Nobel Prize in Physiology or Medicine for 2011"}}</ref>

Dendritic cells were first described by [[Paul Langerhans]] (Langerhans cells) in the late nineteenth century. It wasn't until 1973, however, that [[Ralph Steinman]] and Zanvil  Cohn gave them the name 'dendritic cells'.<ref name=Steinman>{{cite journal |author=Steinman R.M. & Cohn Z.A. |title=Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution |journal=J. Exp. Med. |volume=137 |issue=5 |pages=1142–62 |year=1973 |pmid=4573839|doi=10.1084/jem.137.5.1142 |pmc=2139237}}</ref> For discovering the central role of dendritic cells in the adaptive immune response,<ref name="pmid9521319">{{cite journal |author=Banchereau J. & Steinman R.M. |title=Dendritic cells and the control of immunity |url=https://archive.org/details/sim_nature-uk_1998-03-19_392_6673/page/244 |journal=Nature |volume=392 |issue=6673 |pages=245–52 |year=1998 |pmid=9521319 |doi=10.1038/32588 |s2cid=4388748 }}</ref> Steinman was awarded the [[Albert Lasker Award]] in 2007,<ref name="Lasker2007">{{cite web |url=http://www.laskerfoundation.org/awards/2007basic.htm |title=The Lasker Foundation - 2007 Awards |access-date=2010-11-27}}</ref> and the [[Nobel Prize in Physiology or Medicine]] in 2011.<ref name="Nobel2011">{{cite web |url=http://www.nobelprize.org/nobel_prizes/medicine/laureates/2011/# |title=Nobel Prize in Physiology or Medicine for 2011"}}</ref>

== Dendritic Cell Media ==

== Dendritic Cell Media ==

File:S8-Dendritic Cells Dragging Conidia in Collagen.ogg|A well-resolved dendritic cell drags a [[conidium]] through a distance of up to 9 μm. The conidium, however, is not [[phagocytosis|phagocytosed]] by the cell. The observation was made over 3 h with one frame every 30 s.

File:S8-Dendritic Cells Dragging Conidia in Collagen.ogg|A well-resolved dendritic cell drags a [[conidium]] through a distance of up to 9 μm. The conidium, however, is not [[phagocytosis|phagocytosed]] by the cell. The observation was made over 3 h with one frame every 30 s.

File:S6-Dendritic Cells with Conidia in Collagen.ogv|A single dendritic cell can be seen here efficiently taking up at least four conidia in its vicinity.

File:S6-Dendritic Cells with Conidia in Collagen.webm|A single dendritic cell can be seen here efficiently taking up at least four conidia in its vicinity.

</gallery>

</gallery>

== References ==

== References ==