Uremia

Uremia is a Greek word used in English to describe the condition of a person's blood. Uremia is caused by urine products building up in the blood. If those come over the normal filtration system of the kidneys then the condition is called uremia. People with chronic renal disease or acute renal failure are usually affected by uremia.

Physical signs, symptoms and laboratory findings

Fatigue
Peripheral neuropathy
Anorexia
Decreased sense of smell and taste
Cramps
Restless legs
Sleep disturbances
Coma
Reduced muscle membrane potential
asterixis and tremor
lethargy/deterioration in mental status, encephalopathy, seizures
hyperreflexia and upgoing toes
uremic fetor
pericarditis and/or bruising (from qualitative, not quantitative, platelet dysfunction)
fall in BP and body temperature
nausea/vomiting
Reduced body temperature
Altered amino acid levels
Bone disease due to phosphate retention, hyperparathyroidism, and vitamin D deficiency
Insulin resistance
Increase protein-muscle catabolism
Anemia due to erythropoietin deficiency and shortened red-cell survival