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|Centuries:||15th century – 16th century – 17th century|
|Decades:||1510s 1520s 1530s – 1540s – 1550s 1560s 1570s|
|Years:||1540 1541 1542 1543 1544 1545 1546 1547 1548 1549|
|Categories:|| Births – Deaths – Architecture|
Establishments – Disestablishments
- Hernando de Soto is the first European to see the Mississippi River.
- Ivan IV of Muscovy becomes the first Tsar of Russia.
- Edward VI succeeds his father Henry VIII as King of England.
- Wars between Protestants and Catholics in Europe.
- Japan opens up to Europeans.