Amoxicillin
Expression error: Unexpected < operator.Expression error: Unexpected < operator.Expression error: Unexpected < operator.
 | |
 | |
| Clinical data | |
|---|---|
| Pronunciation | /əˌmɒksɪˈsɪlɪn/ |
| Trade names | Hundreds of names[1] |
| Synonyms | Amoxycillin, amox, Amoxycillin (AAN AU) |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a685001 |
| License data |
|
| Pregnancy category |
|
| Routes of administration | By mouth, intravenous |
| Drug class | β-lactam antibiotic |
| ATC code | |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Bioavailability | 95% by mouth |
| Metabolism | less than 30% biotransformed in liver |
| Elimination half-life | 61.3 minutes |
| Excretion | Kidneys |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| E number | |
| ECHA InfoCard | |
| Chemical and physical data | |
| Formula | C16H19N3O5S |
| Molar mass | 365.40 g·mol−1 |
| 3D model (JSmol) | |
| Density | 1.6±0.1 [2] g/cm3 |
| (verify) | |
Amoxicillin is an antibiotic used to treat some bacterial infections.[3] It is one of the most common antibiotics given to children.[4]
It may be given for middle ear infection, strep throat, pneumonia, skin infections, and urinary tract infections among others.[3] It is taken by mouth, or less commonly by injection.[3][5]
Common bad side effects are nausea and a rash.[3] It can also make yeast infections more likely. When taken with clavulanic acid, it can cause diarrhea.[6] It should not be used on someone allergic to penicillin. [3] It can be used for people with kidney problems, but less should be given than normal.[3] It may be used on pregnant women or women who are breastfeeding.[3]
Amoxicillin was discovered in 1958 and its use started in 1972.[7][8] It is on the (WHO) World Health Organization's List of Essential Medicines.[9]
Amoxicillin Media
Amoxicillin BP
References
- ↑ International brand names for amoxicillin. www.drugs.comDrugs.com. Retrieved 15 November 2016.
- ↑ Amoxicillin. www.chemsrc.com.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Amoxicillin. The American Society of Health-System Pharmacists. Retrieved 1 August 2015.
- ↑ Diseases of the liver and biliary system in children (2008). Chichester, UK: Wiley-Blackwell. p. 217. ISBN 978-1-4443-0054-3.
- ↑ Amoxicillin Sodium for Injection. EMC (10 February 2016). Retrieved 26 October 2016.
- ↑ Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication. CMAJ 187 (1) (January 2016). p. E21–E31. doi:10.1503/cmaj.140848.
- ↑ Analogue-based Drug Discovery (in en) (2006)John Wiley & Sons. p. 490. ISBN 978-3-527-60749-5.
- ↑ An introduction to pharmaceutical sciences production, chemistry, techniques and technology (2012). Cambridge: Woodhead Pub.. p. 239. ISBN 978-1-908818-04-1.
- ↑ World Health Organization model list of essential medicines: 21st list 2019 (2019). Geneva: World Health Organization.