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|Systematic (IUPAC) name|
|ATC code||A01 B01, N02|
|Mol. mass||180.157 g/mol|
|Synonyms|| 2-acetyloxybenzoic acid|
|Melt. point||135 °C (275 °F)|
|Boiling point||140 °C (284 °F) (decomposes)|
|Solubility in water||3 mg/mL (20 °C)|
|Bioavailability||Rapidly and completely absorbed|
|Half life|| 300–650 mg dose: 3.1–3.2 h|
1 g dose: 5 h
2 g dose: 9 h
|Routes||Most commonly oral. Lysine acetylsalicylate may be given IV or IM|
Aspirin (acetylsalicylic acid) is a drug. It is most commonly used as a pain killer, or to reduce fever or inflammation. It also has an anti-platelet effect - it reduces the number of platelets in the blood which reduces blood clotting- in that function it is used to prevent heart attacks. Aspirin is one of the most-used medical drugs in the world.
There are some possible side-effects to this drug. For example, large amounts can damage the kidneys. Children taking aspirin can develop Reye's syndrome which causes the liver to become fatty and not work properly and also the brain to become enlarged. Reyes syndrome can be fatal, but most children survive it with treatment.
People with lung, kidney disease, gout, hyperuricemia (high amounts of uric acid in the blood), hemophilia (a blood clotting disorder), diabetes or high blood pressure should not take aspirin except on the advice of a qualified medical professional. Nor should people who are allergic to it, to ibuprofen or to naproxen. People with asthma where attacks are brought about by aspirin should avoid using any anti-inflammatory drugs based on it.