Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a severe type of muscular dystrophy. The symptom of muscle weakness usually begins around the age of four in boys and worsens quickly. Most are unable to walk by the age of 12. Scoliosis is also common.
The disorder is X-linked recessive. About two thirds of cases are inherited from a person's mother, while one third of cases are due to a new mutation. It is caused by a mutation in the gene for the protein dystrophin.
Although there is no known cure, physical therapy, braces, and corrective surgery may help with some symptoms.[1]
Duchenne Muscular Dystrophy Media
Gowers's sign
DMD is inherited in an X-linked recessive manner.
Depiction of dystrophin connecting intracellular actin to extracellular matrix
Salbutamol (albuterol) — a β2 agonist
Dr Guillaume Duchenne de Boulogne
A simple explanation of how the DNA can be read by the transcription machinery.
References
- ↑ "Muscular Dystrophy: Hope Through Research". NINDS. March 4, 2016. Archived from the original on 30 September 2016. Retrieved 12 September 2016.
