Histiocytosis

Histiocytosis is the name for a medical condition, when a human (or other animal) has too many hystiocytes. Hystiocites are specialized macrophages. Hystiocitosis is also used as a name for a number of diseases, which have this symptom. The diseases are relatively rare, they affect about one to two newborns per million. The WHO has classified the diseases in three groups. There are different forms of chemotherapy, to treat those affected.

Langerhans cell histiocytosis of the bone. Collections of eosinophils and mononuclear Langerhans cells. ×10.

Langerhans cell histiocytosis: Mixed monuclear, histiocytic and giant cells and few eosinophils (HE stain).

Histiocytosis Media

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  Sinus histiocytosis, a common feature in lymph node biopsies, is characterized by dilated sinuses containing variable numbers of histiocytes.