Nephritis

Nephritis is inflammation of the kidneys. It may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules.[1]

Nephritis is often caused by infections, and toxins, but is most commonly caused by autoimmune disorders that affect the major organs like kidneys.[2]

Nephritis can produce glomerular injury, by disturbing the glomerular structure with inflammatory cell proliferation.[3] This can lead to reduced glomerular blood flow, leading to reduced urine output (oliguria)[4] and retention of waste products (uremia).[5] As a result, red blood cells may leak out of damaged glomeruli, causing blood to appear in the urine (hematuria).[6]

Nephritis Media

References

  1. Keto Acids – Advances in Research and Application 2013 Edition p.220e
  2. Acute Nephritis; Nephrosis; Nephritic syndrome information. Patient | Patient. Patient. Retrieved 23 July 2016.
  3. Glomerular Diseases. www.niddk.nih.gov. Retrieved 2015-06-15.
  4. Oliguria: Background, Etiology, Epidemiology. MedscapeeMedicine. Retrieved 23 July 2016.
  5. uremia | accumulation in the blood of constituents normally eliminated in the urine that produces a severe toxic condition and usually occurs in severe kidney disease. www.merriam-webster.com. Retrieved 2015-06-14.
  6. Hematuria (Blood in the Urine). www.niddk.nih.gov. Retrieved 2015-06-14.