Positive-sense single-stranded RNA virus
A positive-sense single-stranded RNA virus (or (+)ssRNA virus) is a virus which has positive sense single stranded RNA as its genetic material. They can be positive or negative. This depends on the polarity of the RNA. The positive-sense viral RNA genome can serve as messenger RNA and can be translated into protein in the host cell.
Many of the known viruses are positive-sense RNA viruses, including the hepacivirus C, West Nile virus, dengue virus, SARS and MERS coronaviruses, and SARS-CoV-2[1] as well as less serious pathogens such as the rhinoviruses that cause the common cold.[2][3][4]
Positive-sense Single-stranded RNA Virus Media
Life cycle of Japanese encephalitis virus a +ssRNA virus: attachment, endocytosis, membrane fusion, uncoating, translation, RNA replication, assembly, maturation, and release.
Mechanisms of replicative and nonreplicative RNA recombination.
Phylogenetic tree with phylum branches highlighted. Negarnaviricota (brown), Duplornaviricota (green), Kitrinoviricota (pink), Pisuviricota (blue), and Lenarviricota (yellow).
False-color Transmission electron micrograph of a SARS-CoV-2 virion. Coronaviruses like SARS-CoV-2 fall in the phylum Pisuviricota.
_(cropped).jpg)
References
- ↑ Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 395 (10224) (February 2020). p. 565–574. doi:10.1016/S0140-6736(20)30251-8.
- ↑ The dependence of viral RNA replication on co-opted host factors. Nature Reviews. Microbiology 10 (2) (December 2011). p. 137–49. doi:10.1038/nrmicro2692.
- ↑ Host factors in positive-strand RNA virus genome replication. Journal of Virology 77 (15) (August 2003). p. 8181–6. doi:10.1128/JVI.77.15.8181-8186.2003.
- ↑ Modrow, Susanne. Molecular virology (2013). Berlin, Heidelberg: Springer. p. 185–349. ISBN 978-3-642-20718-1. doi:10.1007/978-3-642-20718-1_14.