Alprazolam

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Alprazolam
Alprazolam structure.svg
Alprazolam ball-and-stick model.png
Clinical data
PronunciationAlprazolam /ælˈpræzəlæm/ or /ælˈprzəlæm/, Xanax /ˈzænæks/
Trade namesXanax, Xanor, Niravam, others
AHFS/Drugs.comMonograph
MedlinePlusa684001
Pregnancy
category
  • US: D (Evidence of risk)
Dependence
liability
High
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability80–90%
Protein binding80%
MetabolismLiver, via cytochrome P450 3A4
Metabolitesalpha-hydroxyalprazolam, 4-hydroxyalprazolam, beta-hydroxyalprazolam
Onset of actionless than an hour[1]
Elimination half-lifeImmediate release: 4–6 hours
Extended release: 11–16 hours
Duration of action6 hours[1]
ExcretionKidney
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}
Chemical and physical data
FormulaC17H13ClN4
Molar mass308.77 g·mol−1
3D model (JSmol)
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Alprazolam, probably better known by its trade name Xanax, is a short-acting drug. The drug is used to treat people with anxiety disorders and panic attacks. Alprazolam is the most commonly misused benzodiazepine (the drug's class) in the United States; but the majority of prescribed users do not develop a substance-use disorder. Alprazolam is a prescription drug in the United States.

Alprazolam Media

Sources

  1. 1.0 1.1 Lilley, Linda Lane; Snyder, Julie S.; Collins, Shelly Rainforth (2016). Pharmacology for Canadian Health Care Practice. Elsevier Health Sciences. p. 329. ISBN 9781771720663.