Renal cell carcinoma
Renal cell carcinoma is a type of renal cancer (cancer of the kidneys). If it is found early, it can often be cured. However, if the cancer has already spread to other parts of the body, it is much more difficult to treat successfully.
Signs and symptoms
- Pain in the sides of the body)
- Weight loss
- Fever
- Blood in the urine
- A mass that can be felt through the skin
In bad cases, patients may also have symptoms of metastasis (symptoms in other parts of the body where the cancer has spread)
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Renal Cell Carcinoma Media
Generally the cells have a clear cytoplasm, are surrounded by a distinct cell membrane and contain round and uniform nuclei.
Type 1 PRCC consist of papillae covered with a single or double layer of small cuboid cells with scanty cytoplasm and Type 2 PRCC consist of papillae covered by large eosinophilic cells arranged in an irregular or pseudostratified manner.
ChRCC consists of tumor cells with well demarcated borders and abundant pale to eosinophilic cytoplasm.
Renal cell carcinoma*This 8-centimeter carcinoma of the lower pole of the kidney shows extension beyond the cortical surface, but it does not infiltrate the perinephric adipose tissue. Microscopically, it is of the clear cell type. The photo was shot on Kodak Elite transparency film, ISO 200, with a Minolta X-370 and Rokkor f/4 bellow lens.
Histopathologic types of kidney tumor, with relative incidences and prognoses, including renal cell carcinoma and its subtypes
Gross appearance of the cut surface of a nephrectomy specimen containing a large renal cell carcinoma (the large yellowish tumour in the upper half of the kidney).
Micrograph of embolic material in a kidney removed because of renal cell carcinoma (cancer not shown). H&E stain.
Left renal tumor with inferior vena cava thrombus into the right atrium
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