Irwin Fridovich
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Irwin Fridovich | |
|---|---|
 Irwin Fridovich in 1994 | |
| Born | August 2, 1929 New York City, New York, U.S. |
| Died | November 2, 2019 (aged 90) Durham, North Carolina, U.S. |
| Citizenship | United States |
| Alma mater | City College of New York (BS 1951), Duke University (PhD 1955) |
| Known for | superoxide dismutase, oxygen free radicals |
| Awards | Elliott Cresson Medal (1997) |
| Scientific career | |
| Fields | Biochemistry |
| Institutions | Duke University |
| Doctoral students | Joe M. McCord, Hara P. Misra |
Irwin Fridovich (August 2, 1929 – November 2, 2019)[1] was an American biochemist. He discovered the enzymatic activity of copper,zinc superoxide dismutase (SOD),[2][3]—to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism.[4]
He spent the rest of his career studying the biochemical mechanisms.[5][6][7] Fridovich was also Professor Emeritus of Biochemistry at Duke University.
Irwin Fridovich Media
Ribbon drawing of the subunit 3D structure of Cu,Zn superoxide dismutase
References
- ↑ Duke Flags Lowered: Biochemist Irwin Fridovich Dies at Age 90.
- ↑ Superoxide Dismutase, An Enzymic Function for Erythrocuprein (Hemocuprein). Journal of Biological Chemistry 244 (22) (1969). p. 6049–6055. doi:10.1016/S0021-9258(18)63504-5.
- ↑ Fridovich I. The trail to superoxide dismutase. Protein Science 7 (12) (1998). p. 2688–2690. doi:10.1002/pro.5560071225.
- ↑ Isolation and characterization of superoxide dismutase: a personal history and tribute to Joe McCord and Irwin Fridovich. Free Radical Biology and Medicine 5 (5–6) (1988). p. 371–6. doi:10.1016/0891-5849(88)90110-4.
- ↑ Fridovich I. The biology of oxygen radicals. Science 201 (4359) (1978). p. 875–880. doi:10.1126/science.210504.
- ↑ Fridovich I. Superoxide radical and superoxide dismutases. Annual Review of Biochemistry 64 (1995). p. 97–112. doi:10.1146/annurev.bi.64.070195.000525.
- ↑ Kresge N, Simoni RD, Hill RL. Forty Years of Superoxide Dismutase Research: the Work of Irwin Fridovich (JBC Classics: Enzymology). The Journal of Biological Chemistry 281 (22) (2006). p. e17. doi:10.1016/S0021-9258(20)56010-9. Retrieved July 3, 2011.
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