Monkeypox virus

Monkeypox virus (MPV or MPXV) is a double-stranded DNA, zoonotic virus that causes monkeypox in humans and other animals. It belongs to the genus Orthopoxvirus in the family Poxviridae. It is not related to smallpox. Monkeypox disease is similar to smallpox, but with a milder rash and lower death rate.^[1]^[2]^[3]

Monkeypox Virus Media

Schematic illustration of monkeypox, HIV, SARS CoV-2, and polio viruses, drawn to scale. Membranes and membrane-bound proteins are in purple, capsids are in dark blue, and genomes and nucleoid-associated proteins are in turquoise.
Colorized transmission electron micrograph of monkeypox virus particles (green)
Transmission scheme of the monkeypox virus
World map showing spread of monkeypox by virus clade, using national borders.*Data: * Africa/endemic disease:* * [1] African nations affected and clades * [2] verification of African clades * 2022 outbreak:* * [3] initial nations outside of Africa affected * [4] further updateLast updated 2022-06-17 1100hrs UTC * Base:
BlankMap-World.svg No known cases Endemic West African clade Endemic Congo Basin (Central African) clade Both clades recorded West African clade outbreak in 2022 Suspected cases

References

↑ Breman JG, Kalisa R, Steniowski MV, Zanotto E, Gromyko AI, Arita I (1980). "Human monkeypox, 1970-79". Bull World Health Organ. 58 (2): 165–182. PMC 2395797. PMID 6249508.
↑ Alkhalil Abdulnaser; Hammamieh Rasha; Hardick Justin; Ichou Mohamed A; Jett Marti; Ibrahim Sofi (2010). "Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactions". Virology Journal. 7: 173. doi:10.1186/1743-422X-7-173. PMC 2920256. PMID 20667104.
↑ Shchelkunov SN, Totmenin AV, Safronov PF, Mikheev MV, Gutorov VV, Ryazankina OI, Petrov NA, Babkin IV, Uvarova EA, Sandakhchiev LS, et al. (2002). "Analysis of the monkeypox virus genome". Virology. 297 (2): 172–194. doi:10.1006/viro.2002.1446. PMC 9534300. PMID 12083817.

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[Breman_JG_1980-1] Breman JG, Kalisa R, Steniowski MV, Zanotto E, Gromyko AI, Arita I (1980). "Human monkeypox, 1970-79". Bull World Health Organ. 58 (2): 165–182. PMC 2395797. PMID 6249508.

[2] Alkhalil Abdulnaser; Hammamieh Rasha; Hardick Justin; Ichou Mohamed A; Jett Marti; Ibrahim Sofi (2010). "Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactions". Virology Journal. 7: 173. doi:10.1186/1743-422X-7-173. PMC 2920256. PMID 20667104.

[3] Shchelkunov SN, Totmenin AV, Safronov PF, Mikheev MV, Gutorov VV, Ryazankina OI, Petrov NA, Babkin IV, Uvarova EA, Sandakhchiev LS, et al. (2002). "Analysis of the monkeypox virus genome". Virology. 297 (2): 172–194. doi:10.1006/viro.2002.1446. PMC 9534300. PMID 12083817.

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